Description

2-Amino-4'-Trifluoromethylacetophenone Hydrochloride is a high-purity organic intermediate characterized by its trifluoromethyl and amino functional groups. This compound is valued for its role as a critical building block in the synthesis of more complex, high-value molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers in the fine chemical and pharmaceutical industries for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

This versatile chemical intermediate serves as a key precursor in several advanced synthetic pathways. Its primary and potential applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and other functional materials with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and as a ligand precursor in catalytic systems.

Basic Information

Product Name	2-Amino-4'-Trifluoromethylacetophenone Hydrochloride
CAS No.	339-58-2
Molecular Formula	C9H8F3NO • HCl
Molecular Weight	239.62 g/mol (Free base: 203.16 g/mol)
Synonyms	1-(4-(Trifluoromethyl)phenyl)-2-aminoethanone hydrochloride; 2-Amino-1-[4-(trifluoromethyl)phenyl]ethanone hydrochloride; 4'-Trifluoromethyl-2-aminoacetophenone HCl; α-Amino-4'-(trifluoromethyl)acetophenone hydrochloride; 2-Amino-4'-trifluoromethyl acetophenone HCl; TFMPAA HCl; ATAP HCl
EINECS	Contact for details

Quality Control

Our 2-Amino-4'-Trifluoromethylacetophenone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.