Description

8-Fluoro-3-oxooctanoic acid ethyl ester is a high-purity fluorinated ketoester building block, essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a reactive β-ketoester moiety with a strategically placed fluorine atom, enabling precise chemical modifications. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for exploring new fluorination reactions and constructing complex molecular scaffolds.
• Material Science: Potential intermediate for synthesizing specialty polymers and advanced materials with tailored surface properties.
• Fluorine Chemistry: A valuable reagent for studying the effects of fluorine substitution on reaction pathways and physicochemical properties in organic molecules.

Basic Information

Product Name	8-Fluoro-3-oxooctanoic Acid Ethyl Ester
CAS No.	333-56-2
Molecular Formula	C10H17FO3
Molecular Weight	204.24 g/mol
Synonyms	Ethyl 8-Fluoro-3-oxooctanoate; 8-Fluoro-3-oxooctanoic Acid Ethyl Ester; 3-Oxooctanoic Acid, 8-Fluoro-, Ethyl Ester; Ethyl 8-Fluoro-3-oxocaprylate; 8-Fluoro-β-ketooctanoic Acid Ethyl Ester; FKOE (abbreviation); Octanoic acid, 8-fluoro-3-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 8-Fluoro-3-oxooctanoic acid ethyl ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by GC or HPLC), and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity	Contact for details
Refractive Index	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.