Description

1,1,1-Trifluoro-3-Phenylpropan-2-Ol is a versatile fluorinated organic building block of significant interest in advanced chemical synthesis. Its value lies in the unique combination of a phenyl ring and a trifluoromethyl group adjacent to a secondary alcohol, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its impact on molecular polarity and alignment.
• Advanced Polymer Chemistry: Employed to introduce fluorinated side chains into polymers, modifying surface properties, chemical resistance, and thermal stability.
• Asymmetric Synthesis Chiral Building Block: The chiral center makes it valuable for constructing enantiomerically pure compounds in medicinal chemistry and catalysis.
• Fluorine-19 NMR Spectroscopy: Can be used as a reference standard or probe in analytical chemistry due to the distinct NMR signal of its trifluoromethyl group.

Basic Information

Product Name	1,1,1-Trifluoro-3-Phenylpropan-2-Ol
CAS No.	330-72-3
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	1,1,1-Trifluoro-3-phenyl-2-propanol; 3-Phenyl-1,1,1-trifluoro-2-propanol; α-(Trifluoromethyl)benzyl alcohol; 2-Propanol, 1,1,1-trifluoro-3-phenyl-; Benzenemethanol, α-(trifluoromethyl)-; (RS)-1,1,1-Trifluoro-3-phenylpropan-2-ol; (±)-1,1,1-Trifluoro-3-phenyl-2-propanol; F3C-CH(OH)-CH2-Ph
EINECS	206-357-7

Quality Control

Our 1,1,1-Trifluoro-3-Phenylpropan-2-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.