Description

4,4,4-Trifluoro-1-(2-Furyl)-1,3-Butanedione is a versatile fluorinated β-diketone building block characterized by its unique trifluoromethyl and furyl substituents. This compound is highly valued for its role as a key intermediate in the synthesis of complex heterocyclic compounds and advanced materials. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional molecules. Its structural features make it a critical precursor for creating compounds with enhanced biological activity and specific physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Coordination Chemistry & Ligand Design: Serves as a chelating ligand for metal ions, useful in catalysis and the creation of metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and organic electronic materials to modify solubility and electronic properties.
• Chemical Research & Development: A versatile building block for organic synthesis, including cyclization reactions and the preparation of complex heterocycles like furans and pyrazoles.

Basic Information

Product Name	4,4,4-Trifluoro-1-(2-Furyl)-1,3-Butanedione
CAS No.	326-90-9
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	1,1,1-Trifluoro-4-(2-furanyl)-2,4-butanedione; 4,4,4-Trifluoro-1-(2-furyl)butane-1,3-dione; 2-Furoyltrifluoroacetone; FTA; 4,4,4-Trifluoroacetoacetylfuran; Thenoyltrifluoroacetone (related analog); TTA (common abbreviation); β-Diketone fluorinated furan derivative
EINECS	206-322-7

Quality Control

Our 4,4,4-Trifluoro-1-(2-Furyl)-1,3-Butanedione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.