Description

2-Bromo-1-Ethoxy-4-Fluorobenzene is a high-purity halogenated aromatic ether building block of significant importance in advanced organic synthesis. This compound matters because it serves as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromo and fluoro substituents contribute to biological activity.
• Liquid Crystal Materials (LCs): Serves as a core building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport materials and host materials for OLED devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Material Science Research: Utilized in the synthesis of novel polymers and organic semiconductors with tailored electronic properties.

Basic Information

Product Name	2-Bromo-1-Ethoxy-4-Fluorobenzene
CAS No.	326-69-2
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-Bromo-2-ethoxy-4-fluorobenzene; 2-Bromo-4-fluoroanisole; 4-Fluoro-2-bromoanisole; 2-Bromo-4-fluorophenetole; 4-Fluoro-2-bromophenetole; 2-Bromo-1-ethoxy-4-fluorobenzene; 2-Bromo-4-fluoro-1-ethoxybenzene; 326-69-2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Ethoxy-4-Fluorobenzene is produced under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.5 g/cm³
Refractive Index (n20D)	~1.52

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.