Description

4,4,4-Trifluoro-2-Methyl-1-Phenyl-Butane-1,3-Dione is a high-purity fluorinated β-diketone building block. This compound is valued for its unique trifluoromethyl group, which imparts significant chemical and metabolic stability to advanced materials and active pharmaceutical ingredients. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in CNS and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the CF3 group improves lipophilicity and biological activity.
• Ligand Precursor: Serves as a starting material for the synthesis of β-diketonate ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of fluorinated polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile fluorinated building block for heterocyclic chemistry and the introduction of the trifluoromethylacetyl moiety.

Basic Information

Product Name	4,4,4-Trifluoro-2-Methyl-1-Phenyl-Butane-1,3-Dione
CAS No.	322-06-5
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	1-Phenyl-4,4,4-trifluoro-2-methylbutane-1,3-dione; 4,4,4-Trifluoro-2-methyl-1-phenyl-1,3-butanedione; 2-Methyl-4,4,4-trifluoro-1-phenyl-1,3-butanedione; 1,3-Butanedione, 4,4,4-trifluoro-2-methyl-1-phenyl-; Benzoyltrifluoroacetone, 2-methyl-; 2-Methylbenzoyltrifluoroacetone; α-Methyl-4,4,4-trifluoro-1-phenyl-1,3-butanedione; TTA (context-specific)
EINECS	206-285-5

Quality Control

Our 4,4,4-Trifluoro-2-Methyl-1-Phenyl-Butane-1,3-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.