Description

Ethanone, 2-Bromo-2-Fluoro-1-Phenyl- (9Ci) CAS NO 321-75-5 is a specialized halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a versatile reagent for introducing fluorinated motifs and facilitating key transformations like nucleophilic substitutions. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in CNS and anti-inflammatory research.
• Agrochemical Synthesis: Building block for developing novel herbicides and pesticides with enhanced biological activity and environmental stability.
• Material Science Research: Used in the development of specialty polymers and liquid crystals where fluorine incorporation modifies material properties.
• Fluorination Reagent: Acts as a source of a fluorinated acetyl group in complex molecule construction.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed reactions for carbon-carbon bond formation.
• Academic & R&D: Valuable tool in methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Ethanone, 2-Bromo-2-Fluoro-1-Phenyl- (9Ci)
CAS No.	321-75-5
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2-Bromo-2-fluoroacetophenone; α-Bromo-α-fluoroacetophenone; 2-Fluoro-2-bromo-1-phenylethanone; 1-Phenyl-2-bromo-2-fluoroethanone; (2-Bromo-2-fluoroacetyl)benzene; Bromofluoroacetophenone; Phenacyl bromide, 2-fluoro-; NSC 406906
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-2-fluoroacetophenone is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.