Description

4-Chloro-2-(Trifluoromethyl)Benzaldehyde is a versatile halogenated aromatic aldehyde building block. Its molecular structure, featuring both chloro and trifluoromethyl substituents, is critical for imparting unique electronic and steric properties in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors. It serves as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Functional Dyes & Pigments: Employed in the synthesis of specialized dyes and pigments with enhanced light-fastness and unique chromatic properties.
• Cross-Coupling Reactions: The aldehyde group is a reactive handle for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex molecules, including ligands for catalysis and supramolecular chemistry.

Basic Information

Item	Details
Product Name	4-Chloro-2-(Trifluoromethyl)Benzaldehyde
CAS No.	320-43-4
Molecular Formula	C8H4ClF3O
Molecular Weight	208.56 g/mol
Synonyms	4-Chloro-α,α,α-trifluoro-o-tolualdehyde; 2-(Trifluoromethyl)-4-chlorobenzaldehyde; 4-Chloro-2-trifluoromethylbenzaldehyde; 4-Chloro-α,α,α-trifluoro-2-methylbenzaldehyde; Benzaldehyde, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-α,α,α-trifluoro-o-toluic aldehyde
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Trifluoromethyl)Benzaldehyde adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality systems are designed to meet the rigorous demands of GMP and ISO standards for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (nitrogen or argon) to preserve purity and prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.