Description

4-Chloro-1,2-Bis-(Trifluoromethyl)Benzene is a high-value, multi-functional fluorinated aromatic building block. This compound matters for its unique combination of a chloro substituent and two trifluoromethyl groups, which impart exceptional chemical stability, lipophilicity, and electronic properties. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring enhanced metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorine-containing liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitutions as a versatile electrophile or as a source of a fluorinated aryl moiety.
• Dye & Pigment Intermediate: Employed in the synthesis of high-performance, light-fast fluorinated dyes and pigments.

Basic Information

Product Name	4-Chloro-1,2-Bis-(Trifluoromethyl)Benzene
CAS No.	320-30-9
Molecular Formula	C8H3ClF6
Molecular Weight	248.55 g/mol
Synonyms	1-Chloro-3,4-Bis(trifluoromethyl)benzene; 3,4-Bis(trifluoromethyl)chlorobenzene; 4-Chloro-1,2-bis(trifluoromethyl)benzene; 3,4-Bis(trifluoromethyl)phenyl chloride; α,α,α,α',α',α'-Hexafluoro-4-chloro-o-xylene; 320-30-9; 4-Chloro-α,α,α,α',α',α'-hexafluoro-o-xylene
EINECS	206-274-9

Quality Control

Our 4-Chloro-1,2-Bis-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.