Description

1,2-Dichloro-4,5-Bis-(Trifluoromethyl)Benzene is a high-value, multi-functional fluorinated aromatic building block. Its unique structure, featuring both chlorine and trifluoromethyl substituents, makes it an essential intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group is critical for activity.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to better performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart desirable properties such as chemical resistance, low surface energy, and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution due to the activated chlorine atoms.
• Chemical Research & Development: A versatile scaffold for exploring new chemical entities in academic and industrial R&D settings.

Basic Information

Product Name	1,2-Dichloro-4,5-Bis-(Trifluoromethyl)Benzene
CAS No.	320-22-9
Molecular Formula	C8H2Cl2F6
Molecular Weight	283.00 g/mol
Synonyms	1,2-Dichloro-4,5-bis(trifluoromethyl)benzene; 4,5-Bis(trifluoromethyl)-1,2-dichlorobenzene; 1,2-Dichlorotetrafluoroxylene; Benzene, 1,2-dichloro-4,5-bis(trifluoromethyl)-; 320-22-9; NSC 405124; 3,4-Dichloro-α,α,α,α',α',α'-hexafluoro-o-xylene; 1,2-Dichloro-4,5-di(trifluoromethyl)benzene
EINECS	206-272-4

Quality Control

Our 1,2-Dichloro-4,5-Bis-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.