Description

1-Methyl-3-(Trifluoroacetyl)-1H-Indole is a versatile and high-value indole derivative characterized by its trifluoroacetyl functional group. This compound serves as a critical synthetic intermediate and building block in advanced organic synthesis, particularly for the construction of complex heterocyclic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing indole or trifluoromethyl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the trifluoroacetyl group can influence bioavailability and stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and advanced organic materials with unique electronic or optical properties.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoroacetyl group into target molecules, enabling the study of fluorine's effects on molecular behavior.
• Dye and Pigment Synthesis: Intermediate in the production of specialized indole-based dyes and functional colorants.
• Academic & R&D: Used in university and corporate research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	1-Methyl-3-(Trifluoroacetyl)-1H-Indole
CAS No.	318-54-7
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	3-(Trifluoroacetyl)-1-methylindole; 1-Methyl-3-trifluoroacetylindole; N-Methyl-3-trifluoroacetylindole; 1H-Indole-3-carboxaldehyde, 1-methyl-, 3-(trifluoroacetyl) deriv.; 318-54-7; 1-Methylindole-3-trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-(Trifluoroacetyl)-1H-Indole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.