Description

4-Fluoro-1-Acetonaphthone is a high-purity fluorinated aromatic ketone, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive acetyl group adjacent to a fluorine-substituted naphthalene ring, enabling precise molecular modifications. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used to develop novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, improving charge transport and thermal stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique optical or chemical resistance properties.
• Organic Synthesis & Catalysis Research: A versatile reagent for Friedel-Crafts acylation and other coupling reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Fluoro-1-Acetonaphthone
CAS No.	316-68-7
Molecular Formula	C₁₂H₉FO
Molecular Weight	188.20 g/mol
Synonyms	1-(4-Fluoronaphthalen-1-yl)ethanone; 4'-Fluoro-1'-acetonaphthone; 1-Acetyl-4-fluoronaphthalene; 4-Fluoro-1-naphthyl methyl ketone; 4-Fluoronaphthalen-1-yl methyl ketone; 4-Fluoro-α-naphthyl methyl ketone; 1-(4-Fluoro-1-naphthyl)ethanone
EINECS	206-274-5

Quality Control

Our 4-Fluoro-1-Acetonaphthone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical specifications. Our quality commitment ensures material consistency and reliability for your sensitive synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.