Description

2,2,2-Trifluoro-2',4',6'-Trimethylacetophenone is a high-purity fluorinated aromatic ketone, a key building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl group, which is critical for modifying the physical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the preparation of fluorinated drug candidates, particularly in CNS and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where fluorine incorporation enhances efficacy and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Advanced Polymer Chemistry: Acts as a monomer or modifier to introduce fluorine into polymer backbones, improving chemical resistance and thermal stability.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport materials and host materials for OLED devices.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating novel chemical entities in academic and industrial R&D.

Basic Information

Product Name	2,2,2-Trifluoro-2',4',6'-Trimethylacetophenone
CAS No.	313-56-4
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	2,2,2-Trifluoro-1-(2,4,6-trimethylphenyl)ethanone; 2,4,6-Trimethyl-α,α,α-trifluoroacetophenone; 1-(2,4,6-Trimethylphenyl)-2,2,2-trifluoroethanone; Mesityl trifluoromethyl ketone; Trifluoroacetylmesitylene; α,α,α-Trifluoro-2',4',6'-trimethylacetophenone; TFTA; 2,4,6-Trimethyl-α,α,α-trifluoroacetophenone
EINECS	206-242-9

Quality Control

Our 2,2,2-Trifluoro-2',4',6'-Trimethylacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.