Description

Paraoxon is a highly specific and potent organophosphate compound widely recognized for its role as a biochemical tool and research standard. Its primary value lies in its potent and irreversible inhibition of acetylcholinesterase (AChE), making it a critical reference compound in toxicological, pharmacological, and environmental studies. This product is essential for researchers and laboratories in the agrochemical, pharmaceutical, and life sciences sectors who require a high-purity standard for enzyme inhibition assays, metabolic studies, and the development of detection methods or antidotes.

Application

• Biochemical Research: Used as a standard inhibitor in acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition assays to study enzyme kinetics and mechanisms.
• Toxicology Studies: Serves as a reference toxicant in research on organophosphate poisoning, neurotoxicity, and the development of therapeutic countermeasures.
• Analytical Standard: Employed as a certified reference material (CRM) for the calibration of analytical equipment (GC, LC-MS) in environmental and forensic analysis to detect pesticide metabolites.
• Agrochemical Development: Used in the research and development of pesticides and insecticides to understand metabolic activation pathways and structure-activity relationships.
• Pharmacology: Applied in studies investigating the cholinergic system and for evaluating the efficacy of novel reactivators or prophylactics against nerve agent exposure.
• Environmental Science: Utilized in studies monitoring the degradation and persistence of organophosphate compounds in various ecosystems.

Basic Information

Product Name	Paraoxon
CAS No.	311-45-5
Molecular Formula	C10H14NO6P
Molecular Weight	275.20 g/mol
Synonyms	Diethyl 4-nitrophenyl phosphate; Phosphoric acid, diethyl 4-nitrophenyl ester; E 600; Paraoxon-ethyl; Mintacol; Miotisal; Etilon; Fosfakol; Nitrostigmin
EINECS	206-224-3

Quality Control

Our Paraoxon is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods and precise quantification of the active component. A Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation. Handle and store in accordance with all applicable safety regulations for toxic organophosphates.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.