Description

Benzonitrile, 2-(2-Methylpropoxy)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, synthetically versatile boronic ester derivative. This compound matters as a critical building block in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules. Its specific substitution pattern offers unique reactivity and selectivity profiles for targeted molecular assembly.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic coupling.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs, OFETs, and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules or creating fluorescent probes and sensors for research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	Benzonitrile, 2-(2-Methylpropoxy)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2828446-41-7
Molecular Formula	C17H24BNO3
Molecular Weight	301.19 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-isobutoxybenzonitrile; 2-Isobutoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2-(2-Methylpropoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; PINACOL (2-CYANO-5-ISO-BUTOXYPHENYL)BORONATE; (2-Cyano-5-isobutoxyphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-(2-Methylpropoxy)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring material that meets stringent internal specifications aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.