Description

Potassium (2-Chloro-4-Fluorobenzyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, moisture-stable precursors for palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for creating novel active pharmaceutical ingredients (APIs), especially those containing complex fluorinated and chlorinated aromatic scaffolds.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated aromatic motifs.
• Material Science Research: Serves as a precursor for synthesizing organic electronic materials, liquid crystals, and polymers with tailored properties.
• Suzuki-Miyaura Cross-Coupling: Functions as a stable, easy-to-handle organoboron reagent in palladium-catalyzed carbon-carbon bond formation reactions, offering advantages over traditional boronic acids.
• Library Synthesis for Drug Discovery: Enables the rapid parallel synthesis of diverse compound libraries for high-throughput screening in medicinal chemistry.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Potassium (2-Chloro-4-Fluorobenzyl)Trifluoroborate
CAS No.	2828444-60-4
Molecular Formula	C7H5BClF4K
Molecular Weight	249.47 g/mol
Synonyms	Potassium (2-Chloro-4-fluorophenyl)methyltrifluoroborate; Potassium [(2-Chloro-4-fluorophenyl)methyl]trifluoroboranuide; (2-Chloro-4-Fluorobenzyl)Trifluoroborate Potassium Salt; Potassium Trifluoro(2-chloro-4-fluorobenzyl)borate; 2-Chloro-4-fluorobenzyltrifluoroboronate Potassium; K-2-Chloro-4-fluorobenzyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium (2-Chloro-4-Fluorobenzyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting cGMP and ISO standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain long-term stability. Recommended storage temperature: 2-8°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
NMR Purity (1H, 19F)	≥ 97%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.