Description

Potassium Trifluoro(4-Fluoro-2-Methylbenzyl)Borate is a specialized organoboron reagent, specifically a potassium trifluoroborate salt, valued for its enhanced stability and handling properties compared to boronic acids. This compound serves as a critical coupling partner in modern cross-coupling reactions, enabling the efficient synthesis of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel fluorinated aromatic scaffolds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this fluorinated benzyl building block.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs) containing fluorinated and methyl-substituted benzyl motifs.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides where the specific fluorine substitution pattern can influence bioactivity and metabolic stability.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands or organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into the synthesis of organic electronic materials, such as OLED or OFET components, where fluorination modulates electronic properties.
• Chemical Biology Probes: Useful for tagging molecules or creating bioconjugates for imaging and diagnostic applications due to its robust coupling chemistry.

Basic Information

Product Name	Potassium Trifluoro(4-Fluoro-2-Methylbenzyl)Borate
CAS No.	2828444-52-4
Molecular Formula	C8H8BF4K
Molecular Weight	222.06 g/mol
Synonyms	Potassium (4-Fluoro-2-methylbenzyl)trifluoroborate; (4-Fluoro-2-methylbenzyl)trifluoroboronic acid potassium salt; Potassium (4-Fluoro-2-methylphenyl)methyltrifluoroborate; 4-Fluoro-2-methylbenzyltrifluoroborate potassium salt; Potassium Trifluoro[(4-fluoro-2-methylphenyl)methyl]borate; K-4-F-2-Me-BnBF3; (4-Fluoro-2-methylbenzyl)-BF3K
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(4-Fluoro-2-Methylbenzyl)Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
19F NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.