Description

5-(Benzyloxy)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-value, multifunctional organic building block that combines a benzaldehyde core with a benzyl-protected phenol and a pinacol boronate ester. This compound matters for its versatility as a key intermediate in modern synthetic chemistry, enabling precise carbon-carbon bond formation and complex molecular assembly. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for constructing complex molecules via cross-coupling reactions like the Suzuki-Miyaura reaction.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aromatic architectures.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Cross-Coupling Reactions: The pinacol boronate ester group makes it an ideal partner for Suzuki-Miyaura cross-coupling, a cornerstone reaction for forming carbon-carbon bonds.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands or organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	5-(Benzyloxy)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	2695516-89-1
Molecular Formula	C20H23BO4
Molecular Weight	338.21 g/mol
Synonyms	2-Formyl-4-(benzyloxy)phenylboronic acid pinacol ester; 4-(Benzyloxy)-2-formylphenylboronic acid pinacol ester; 5-(Benzyloxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; Benzaldehyde, 5-(benzyloxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (5-(Benzyloxy)-2-formylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for prolonged periods to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.