Description

3-Pyrrolidinecarboxaldehyde, 3-(Chloromethyl)-1-(Phenylmethyl)- is a versatile and high-value pyrrolidine-based building block, essential for advanced organic synthesis. Its bifunctional structure, featuring both a reactive aldehyde and a chloromethyl group, makes it a critical intermediate for constructing complex nitrogen-containing heterocycles. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and specialized ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic scaffold.
• Ligand & Catalyst Development: Serves as a foundational structure for creating chiral ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Useful for designing molecular probes and inhibitors for biological target studies.
• Custom Synthesis Projects: A valuable starting material for contract research organizations (CROs) and CDMOs working on bespoke chemical entities.

Basic Information

Product Name	3-Pyrrolidinecarboxaldehyde, 3-(Chloromethyl)-1-(Phenylmethyl)-
CAS No.	2654084-04-3
Molecular Formula	C13H16ClNO
Molecular Weight	237.73 g/mol
Synonyms	1-Benzyl-3-(chloromethyl)pyrrolidine-3-carboxaldehyde; 3-(Chloromethyl)-1-benzyl-3-pyrrolidinecarboxaldehyde; 1-(Phenylmethyl)-3-(chloromethyl)-3-pyrrolidinecarboxaldehyde; 3-(Chloromethyl)-1-benzylpyrrolidine-3-carbaldehyde; N-Benzyl-3-(chloromethyl)pyrrolidine-3-carboxaldehyde; 3-Pyrrolidinecarboxaldehyde, 3-(chloromethyl)-1-(phenylmethyl)-; 2654084-04-3; 1-Benzyl-3-(chloromethyl)-3-formylpyrrolidine
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxaldehyde, 3-(Chloromethyl)-1-(Phenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.