Description

1,3,2-Dioxaborolane, 2-[8-Fluoro-3-(Methoxymethoxy)-1-Naphthalenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester derivative designed for sophisticated organic synthesis. This compound matters as a critical building block for constructing complex molecules, particularly in pharmaceutical research and materials science. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for cross-coupling reactions and other transformative chemical processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex naphthalene and fluorine motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile organoboron reagent for forming carbon-carbon bonds in the construction of complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Materials Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure can influence charge transport properties.
• Chemical Biology & Probe Development: Utilized as a building block for creating molecular probes and bioconjugation reagents due to the reactivity of the boronic ester group.
• Process Chemistry & Scale-up: Suitable for use in route development and optimization for the commercial-scale manufacturing of fine chemicals.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[8-Fluoro-3-(Methoxymethoxy)-1-Naphthalenyl]-4,4,5,5-Tetramethyl-
CAS No.	2621936-17-0
Molecular Formula	C₁₈H₂₄BFO₄
Molecular Weight	334.19 g/mol
Synonyms	8-Fluoro-3-(methoxymethoxy)-1-naphthaleneboronic acid pinacol ester; 2-(8-Fluoro-3-(methoxymethoxy)naphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (8-Fluoro-3-(methoxymethoxy)naphthalen-1-yl)boronic acid pinacol ester; 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-fluoro-3-(methoxymethoxy)naphthalene; Fluorinated MOM-protected naphthalene boronic ester; CAS 2621936-17-0
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[8-Fluoro-3-(Methoxymethoxy)-1-Naphthalenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.