Description

1,3,2-Dioxaborolane, 2-[8-Ethyl-3-(Methoxymethoxy)-1-Naphthalenyl]-4,4,5,5-Tetramethyl- is a sophisticated naphthalene-derived boronic ester building block, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon and carbon-heteroatom bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This high-purity intermediate is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures. Its design offers enhanced stability and reactivity for demanding synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific naphthalene-based structures.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, light-emitting materials, and charge-transport layers in electronic devices.
• Ligand & Catalyst Design: Employed in the development of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or functionalization agent for producing specialty polymers with tailored properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[8-Ethyl-3-(Methoxymethoxy)-1-Naphthalenyl]-4,4,5,5-Tetramethyl-
CAS No.	2621932-60-1
Molecular Formula	C₂₂H₃₁BO₄
Molecular Weight	370.29 g/mol
Synonyms	8-Ethyl-3-(methoxymethoxy)-1-naphthaleneboronic acid pinacol ester; 2-(8-Ethyl-3-(methoxymethoxy)naphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (8-Ethyl-3-(methoxymethoxy)naphthalen-1-yl)boronic acid pinacol ester; MOM-Protected Naphthalene Boronic Ester; 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-ethyl-3-(methoxymethoxy)naphthalene; CAS 2621932-60-1
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[8-Ethyl-3-(Methoxymethoxy)-1-Naphthalenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and desiccated. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.