Description

Benzoic Acid, 4-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biphenyl or substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes.
• Academic & Industrial R&D: Fundamental reagent for methodological development and library synthesis in medicinal and combinatorial chemistry.

Basic Information

Product Name	Benzoic Acid, 4-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	2617701-40-1
Molecular Formula	C14H18BClO4
Molecular Weight	296.55 g/mol
Synonyms	Methyl 4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester; 2-Borono-4-chlorobenzoic Acid Methyl Ester, Pinacol Ester; (4-Chloro-2-(methoxycarbonyl)phenyl)boronic Acid Pinacol Ester; Methyl 4-Chloro-2-boronobenzoate Pinacol Ester; CAS 2617701-40-1
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, critical for sensitive cross-coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant regulatory frameworks for advanced intermediates, including REACH and cGMP where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and stored away from direct light to maintain stability and purity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.