Description

1-[4-(Dimethylphosphoryl)Phenyl]Ethan-1-One is a high-purity organophosphorus compound featuring a key acetylphenyl scaffold. This specialized chemical serves as a critical advanced intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for medicinal chemists and process development teams engaged in creating novel active ingredients, where its unique phosphoryl group enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and plant growth regulators leveraging its organophosphorus chemistry.
• Ligand & Catalyst Precursor: Serves as a precursor for sophisticated phosphine-based ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high-purity, structurally complex intermediates.

Basic Information

Product Name	1-[4-(Dimethylphosphoryl)Phenyl]Ethan-1-One
CAS No.	2551117-86-1
Molecular Formula	C10H13O2P
Molecular Weight	196.18 g/mol
Synonyms	4-Acetylphenyl Dimethylphosphinate; 1-[4-(Dimethoxyphosphoryl)phenyl]ethanone; 4-Acetyldimethylphosphinoylbenzene; Dimethyl (4-acetylphenyl)phosphinate; 4-Acetylphenylphosphonic Acid Dimethyl Ester; p-Acetylphenyl Dimethylphosphinate; (4-Acetylphenyl)dimethylphosphine Oxide
EINECS	Contact for details

Quality Control

Our 1-[4-(Dimethylphosphoryl)Phenyl]Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.