Description

2-Methoxy-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Ethanamine is a high-value, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aryl/heteroaryl groups in drug discovery and process chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific aryl-boronate motifs.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of probes and linkers for studying biological processes and protein interactions.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	2-Methoxy-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Ethanamine
CAS No.	2490665-88-6
Molecular Formula	C18H30BNO3
Molecular Weight	319.25 g/mol
Synonyms	2-Methoxy-N-{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}ethanamine; 4-[(2-Methoxyethylamino)methyl]phenylboronic acid pinacol ester; N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methoxyethanamine; 2-Methoxy-N-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl)ethan-1-amine; (4-((2-Methoxyethylamino)methyl)phenyl)boronic acid pinacol ester; CAS 2490665-88-6
EINECS	Contact for details

Quality Control

Our 2-Methoxy-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Ethanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.