Description

(4-((6-Chloro-9H-Purin-9-Yl)Methyl)-Phenyl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for medicinal chemistry. This compound matters for its critical role as a protected boronic acid derivative, enabling key cross-coupling reactions like the Suzuki-Miyaura reaction under mild conditions. It is primarily needed by researchers and manufacturers in pharmaceutical R&D, agrochemical synthesis, and material science for developing novel small-molecule therapeutics and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel purine-based drug candidates, including kinase inhibitors and antiviral agents.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl halides and boronic acids for constructing complex biaryl structures.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Agrochemical Synthesis: Intermediate in the development of new herbicides and fungicides with targeted activity.
• Chemical Biology Probes: Serves as a precursor for creating labeled molecules and probes to study biological pathways.
• Material Science: Building block for organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	(4-((6-Chloro-9H-Purin-9-Yl)Methyl)-Phenyl)Boronic Acid Pinacol Ester
CAS No.	2490665-85-3
Molecular Formula	C19H20BClN4O2
Molecular Weight	382.65 g/mol
Synonyms	6-Chloro-9-[(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)]purine; 2-(4-((6-Chloro-9H-purin-9-yl)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-((6-Chloropurin-9-yl)methyl)phenyl)boronic acid pinacol ester; 6-Chloro-9-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-9H-purine; 9-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-6-chloro-9H-purine; Boronic acid, B-[4-[(6-chloro-9H-purin-9-yl)methyl]phenyl]-, 1,1-dimethylethyl ester; CAS 2490665-85-3
EINECS	Contact for details

Quality Control

Our (4-((6-Chloro-9H-Purin-9-Yl)Methyl)-Phenyl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.