Description

1,3,2-Dioxaborolane, 2-(8-Chloro-1-Naphthalenyl)-4,4,5,5-Tetramethyl- is a high-value, functionalized organoboron reagent, specifically a pinacol-protected naphthylboronic ester derivative. This compound is a critical synthetic intermediate, prized for its stability and reactivity in cross-coupling reactions, which are foundational to modern pharmaceutical and advanced materials chemistry. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and organic electronics industries who require precise and reliable building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing complex biaryl or naphthalene scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate chlorinated naphthalene motifs for enhanced biological activity.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials where the naphthalene unit contributes to charge transport and luminescent properties.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis or as a boronate ester component in metal-organic frameworks (MOFs) and polymeric materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and constructing complex organic molecules for various applications.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(8-Chloro-1-Naphthalenyl)-4,4,5,5-Tetramethyl-
CAS No.	2454397-84-1
Molecular Formula	C16H20BClO2
Molecular Weight	290.59 g/mol
Synonyms	8-Chloro-1-naphthaleneboronic acid pinacol ester; (8-Chloronaphthalen-1-yl)boronic acid pinacol ester; 2-(8-Chloro-1-naphthalenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-chloronaphthalene; 8-Chloro-1-naphthylboronic acid pinacol ester; 8-Chloro-1-boronaphthalene pinacol ester; Pinacol (8-chloro-1-naphthyl)boronate
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborolane, 2-(8-Chloro-1-Naphthalenyl)-4,4,5,5-Tetramethyl- adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.