Description

2’,3’-Di-o-Acetyl-8-Benzyloxy-3’-Deoxy Guanosine is a sophisticated nucleoside derivative, a key building block in advanced pharmaceutical and biochemical research. This compound is critical for the synthesis and development of novel antiviral agents and modified oligonucleotides, where precise molecular structure is paramount. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase or solution-phase synthesis of modified DNA/RNA sequences.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and polymerase activity.
• Prodrug Development: The acetyl and benzyl protecting groups make it a candidate for prodrug strategies to enhance drug delivery and bioavailability.
• Antisense Technology: Employed in the creation of antisense oligonucleotides for therapeutic and diagnostic applications.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2’,3’-Di-o-Acetyl-8-Benzyloxy-3’-Deoxy Guanosine
CAS No.	2389988-71-8
Molecular Formula	C21H23N5O7
Molecular Weight	457.44 g/mol
Synonyms	8-Benzyloxy-2',3'-di-O-acetyl-3'-deoxyguanosine; 3'-Deoxy-2',3'-di-O-acetyl-8-benzyloxyguanosine; Guanosine, 8-(benzyloxy)-2',3'-di-O-acetyl-3'-deoxy-; 8-Bn-2',3'-di-OAc-3'-dG
EINECS	Contact for details

Quality Control

Our 2’,3’-Di-o-Acetyl-8-Benzyloxy-3’-Deoxy Guanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.