Description

1H-Benzotriazole-7-Boronic Acid Picol Ester is a high-value, advanced pharmaceutical intermediate and coupling reagent. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing benzotriazole and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a stable, reactive boronic ester partner for palladium-catalyzed carbon-carbon bond formation in complex molecule assembly.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and emissive layers for electronic devices.
• Chemical Biology & Proteolysis-Targeting Chimeras (PROTACs): A valuable linker or component in the design of bifunctional molecules for targeted protein degradation.
• Academic & Contract Research: Essential reagent for methodological development and synthetic chemistry research in university and CRO laboratories.

Basic Information

Product Name	1H-Benzotriazole-7-Boronic Acid Picol Ester
CAS No.	2379560-98-0
Molecular Formula	C₁₃H₁₁BN₄O₂
Molecular Weight	266.06 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzotriazole; 1H-Benzotriazol-7-ylboronic acid pinacol ester; Benzotriazol-7-ylboronic Acid Pinacol Ester; 7-Boronobenzotriazole Pinacol Ester; 7-(Pinacolatoboryl)-1H-benzotriazole; 7-BBT Pinacol Ester; 1H-Benzo[d][1,2,3]triazol-7-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1H-Benzotriazole-7-Boronic Acid Picol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.