Description

2-Hydroxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-value, multifunctional aromatic aldehyde containing a protected boronic ester group. This compound serves as a versatile and critical building block in modern synthetic chemistry, enabling the construction of complex molecular architectures through cross-coupling and other transformations. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific borylated aromatic structures.
• Material Science: Building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and molecular probes for imaging and diagnostic applications.
• Polymer Chemistry: Monomer for introducing functional aromatic aldehydes and boronates into specialty polymers and resins.

Basic Information

Product Name	2-Hydroxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	2379560-89-9
Molecular Formula	C13H17BO4
Molecular Weight	248.09 g/mol
Synonyms	6-Formyl-3-hydroxyphenylboronic acid pinacol ester; 2-Hydroxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)salicylaldehyde; 2-Hydroxy-6-(pinacolatoboryl)benzaldehyde; Salicylaldehyde-6-boronic acid pinacol ester; 6-Borono-2-hydroxybenzaldehyde pinacol ester; (6-Formyl-2-hydroxyphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP-like controls for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.