Description

3-Cyano-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value, multi-functional organic building block that combines a benzoic acid core with both cyano and boronic ester functional groups. This unique structure makes it a critical intermediate for the synthesis of complex molecules via cross-coupling reactions, particularly Suzuki-Miyaura coupling. It is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require precise, high-purity intermediates for developing active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that require specific aromatic boronic ester motifs.
• Material Science: Serves as a precursor for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its conjugated system and functional handles.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in bioconjugation and the development of enzyme inhibitors or diagnostic agents.
• Academic & Industrial R&D: A versatile reagent for method development in organic synthesis and catalysis research within university and corporate laboratories.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to create functional polymers with tailored properties.

Basic Information

Product Name	3-Cyano-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	2377611-13-5
Molecular Formula	C15H18BNO4
Molecular Weight	287.12 g/mol
Synonyms	5-Cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 3-Carboxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; Benzoic acid, 3-cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol 3-Cyano-5-boronobenzoate; 3-CN-5-Bpin-Benzoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Cyano-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications like pharmaceutical R&D. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.