Description

{3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-5-Yl}Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecular architectures via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, where its heterocyclic boronic acid structure enables the creation of compounds with specific biological activity.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and sensors, due to its conjugated pyrazolopyridine core.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity ligands for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs producing specialized compounds for client R&D programs.

Basic Information

Product Name	{3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-5-Yl}Boronic Acid
CAS No.	2377610-54-1
Molecular Formula	C7H8BN3O2
Molecular Weight	176.97 g/mol
Synonyms	(3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)boronic acid; 5-Borono-3-methyl-1H-pyrazolo[3,4-b]pyridine; 3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-boronic acid; 3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-ylboronic acid; CAS 2377610-54-1; Boronic acid, B-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-
EINECS	Contact for details

Quality Control

Our {3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-5-Yl}Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.