Description

Methylbis[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Amine CAS NO 2377609-51-1 is a specialized organoboron compound featuring a tertiary amine core flanked by two pinacol boronate ester-functionalized benzyl groups. This unique bifunctional structure makes it a valuable advanced synthetic intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. It is primarily needed by R&D chemists and process development scientists working on Suzuki-Miyaura cross-coupling reactions and the development of novel bioactive molecules or functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring complex, boron-containing scaffolds for targeted drug discovery.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile bis-boronate ester coupling partner for the efficient construction of biaryl and conjugated systems under palladium catalysis.
• Materials Science Research: Used in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its structure can be incorporated into conjugated backbones.
• Ligand and Catalyst Development: The tertiary amine and boronate groups provide handles for creating novel chelating ligands or functional catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes, leveraging boron's utility in bioconjugation and imaging.
• Polymer Chemistry: Functions as a monomer or cross-linking agent for synthesizing specialty polymers with tailored properties.

Basic Information

Product Name	Methylbis[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Amine
CAS No.	2377609-51-1
Molecular Formula	C27H39B2NO4
Molecular Weight	463.22 g/mol
Synonyms	N-Methylbis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]amine; Methylbis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)amine; 4,4'-(Methylazanediyl)bis(methylene)dibenzene-1,4-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); Bis(4-(pinacolatoboryl)benzyl)methylamine; N,N-Bis[4-(pinacolatoboron)benzyl]methylamine; 2377609-51-1; Methylbis(pinacolatoborylbenzyl)amine
EINECS	Contact for details

Quality Control

Our production of Methylbis[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Amine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.