Description

5-Bromo-1-Methylpyrazole-4-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a pyrazole boronic ester derivative, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and heterocyclic compound libraries.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Enables the creation of functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Catalyst & Ligand Development: Used to construct complex, nitrogen-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Detail
Product Name	5-Bromo-1-Methylpyrazole-4-Boronic Acid Pinacol Ester
CAS No.	2377609-16-8
Molecular Formula	C10H16BBrN2O2
Molecular Weight	287.97 g/mol
Synonyms	5-Bromo-1-methyl-1H-pyrazole-4-boronic acid pinacol ester; 1-Methyl-5-bromo-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-bromo-1-methyl-1H-pyrazole; 5-Bromo-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 5-Bromo-1-methylpyrazole-4-boronic acid neopentyl glycol ester (common alternative); 5-Br-1-Me-Pyrazole-4-Bpin
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-1-Methylpyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality control includes HPLC, NMR, and mass spectrometry analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are sealed properly after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.