Description

Methyl 4-Nitro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate CAS NO 2377608-56-3 is a high-value, organoboron building block designed for advanced synthetic chemistry. This compound is critical for enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and agrochemical development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing biphenyl or substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aromatic coupling steps.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize tagged molecules or probes for studying biological pathways and target engagement.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	Methyl 4-Nitro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	2377608-56-3
Molecular Formula	C14H18BNO6
Molecular Weight	307.11 g/mol
Synonyms	Methyl 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-nitrobenzoate; 4-Nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-nitrobenzoic Acid Methyl Ester; Methyl 4-Nitro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate; 2377608-56-3; Pinacol 4-Nitro-2-(Methoxycarbonyl)Phenylboronate; 4-Nitro-2-Boronobenzoic Acid Methyl Ester Pinacol Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Nitro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.