Description

Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazole-6-Carboxylate is a high-value, multi-functional chemical building block that integrates a protected boronic ester with a benzimidazole core. This compound matters for its critical role as a key intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions essential for constructing complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need this reagent for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for constructing biaryl and heterobiaryl systems under mild conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require the benzimidazole pharmacophore.
• Material Science & OLED Development: Acts as a building block for creating organic semiconductors, electron-transport materials, and emissive layers in display technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel N-heterocyclic carbene (NHC) precursors and other specialized ligands for transition metal catalysis.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or for creating fluorescent probes and sensors.

Basic Information

Product Name	Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazole-6-Carboxylate
CAS No.	2377607-24-2
Molecular Formula	C17H23BN2O4
Molecular Weight	330.19 g/mol
Synonyms	Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-6-carboxylate; 4-Pinacolatoboryl-1H-benzimidazole-6-carboxylic acid methyl ester; Methyl 4-(pinacolatoboryl)-1H-benzimidazole-6-carboxylate; 1H-Benzo[d]imidazole-6-carboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; 4-BPin-1H-Benzimidazole-6-carboxylic Acid Methyl Ester; Methyl 4-BPin-1H-benzimidazole-6-carboxylate; CAS 2377607-24-2
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazole-6-Carboxylate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.