Description

4-(n-Cbz-n-Isobutylamino)Phenylbornic Acid, Pinacol Ester is a sophisticated boronic acid pinacol ester derivative, a key building block in modern synthetic organic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for critical cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel active compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Suzuki-Miyaura Coupling Reactions: Serves as a stable organoboron reagent for constructing biaryl and heterobiaryl bonds in drug discovery and material science.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Details
Product Name	4-(n-Cbz-n-Isobutylamino)Phenylbornic Acid, Pinacol Ester
CAS No.	2377607-21-9
Molecular Formula	C24H32BNO4
Molecular Weight	409.33 g/mol
Synonyms	4-[(Benzyloxy)carbonyl(isobutyl)amino]phenylboronic acid pinacol ester; [4-[[(Benzyloxy)carbonyl](2-methylpropyl)amino]phenyl]boronic acid pinacol ester; N-Cbz-N-isobutyl-4-boronophenylaniline pinacol ester; 4-(N-Cbz-N-isobutylamino)benzeneboronic acid pinacol ester; B-[4-[[(Phenylmethoxy)carbonyl](2-methylpropyl)amino]phenyl]boronic acid, 1,1,1',1'-tetramethyl-2,2'-bi-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Every batch of 4-(n-Cbz-n-Isobutylamino)Phenylbornic Acid, Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity, typically meeting standards suitable for research and pharmaceutical development. Our products are supported by comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.