Description

2,4-Dichloro-5-(Trifluoromethoxy)Phenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is specifically designed for R&D chemists and process development scientists working on the synthesis of complex molecules, particularly in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a functionalized phenyl ring system.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the unique properties of the trifluoromethoxy and chloro substituents.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2,4-Dichloro-5-(Trifluoromethoxy)Phenylboronic Acid, Pinacol Ester
CAS No.	2377607-20-8
Molecular Formula	C13H14BCl2F3O3
Molecular Weight	357.97 g/mol
Synonyms	2,4-Dichloro-5-(trifluoromethoxy)benzeneboronic acid pinacol ester; (2,4-Dichloro-5-(trifluoromethoxy)phenyl)boronic acid pinacol ester; 5,5-Dimethyl-2-[2,4-dichloro-5-(trifluoromethoxy)phenyl]-1,3,2-dioxaborinane; 2-(2,4-Dichloro-5-(trifluoromethoxyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,4-Dichloro-α,α,α-trifluoro-5-methoxybenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-(Trifluoromethoxy)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.