Description

Methyl 2-{[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamido}Acetate is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound matters for its critical role in modern synthetic chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those requiring boronic acid/ester chemistry.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile coupling partner for the formation of carbon-carbon bonds, essential for creating biaryl structures in medicinal chemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides that incorporate advanced organic frameworks.
• Material Science: A precursor for organic electronic materials and polymers where specific aromatic architectures are required.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	Methyl 2-{[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamido}Acetate
CAS No.	2377607-09-3
Molecular Formula	C16H22BNO5
Molecular Weight	319.16 g/mol
Synonyms	Methyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]glycinate; Methyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamido)acetate; 2377607-09-3; Glycine, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]-, methyl ester; Methyl 2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)amino)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-{[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamido}Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.