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2-Methoxy-n-Methyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide CAS NO 2377607-01-5


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CAS No.:2377607-01-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Methoxy-n-Methyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity boronic ester derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
  • Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents for target identification and labeling.
  • Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in university and CRO laboratories.
  • Scale-up Process Chemistry: Suitable for process optimization and pilot-scale production of target molecules under cGMP conditions where applicable.

Basic Information

Product Name 2-Methoxy-n-Methyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No. 2377607-01-5
Molecular Formula C16H24BNO5
Molecular Weight 321.18 g/mol
Synonyms 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxy-N-methylbenzamide; 2-Methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 2-Methoxy-N-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; MIDA Boronate Ester Derivative; Arylboronic Acid Pinacol Ester; Suzuki Coupling Reagent; Benzamide, 2-methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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Quality Control

Our 2-Methoxy-n-Methyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support our clients' needs for regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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