Description

3-Benzyloxy-2-Methylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound matters as a critical building block in modern cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced materials chemists for applications in drug discovery, catalyst development, and the synthesis of functional organic compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboronic ester precursor for constructing biaryl and heterobiaryl scaffolds central to active pharmaceutical ingredients (APIs) and functional materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in creating complex aromatic and heteroaromatic systems.
• Agrochemical Research: Serves as a building block for developing new active ingredients with specific biological activities.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysis.
• Material Science: Utilized in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, due to its stable boronic ester functionality.
• Chemical Biology Probes: Acts as a synthetic handle for creating molecules used to study biological processes and protein interactions.

Basic Information

Product Name	3-Benzyloxy-2-Methylphenylboronic Acid Pinacol Ester
CAS No.	2377606-95-4
Molecular Formula	C21H27BO3
Molecular Weight	338.25 g/mol
Synonyms	2-Methyl-3-(phenylmethoxy)phenylboronic Acid Pinacol Ester; (3-(Benzyloxy)-2-methylphenyl)boronic Acid Pinacol Ester; 3-Benzyloxy-2-methylbenzeneboronic Acid Pinacol Ester; 2-Methyl-3-benzyloxyphenylboronic Acid Pinacol Ester; Pinacol [3-(Benzyloxy)-2-methylphenyl]boronate; CAS 2377606-95-4
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-2-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.