Description

1-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Pent-4-En-1-One is a high-value, synthetically versatile organoboron building block. This compound is critical for enabling advanced cross-coupling reactions, particularly in the synthesis of complex pharmaceutical intermediates and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct novel molecular architectures with precision.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for constructing biaryl and conjugated systems in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), especially those containing complex aromatic ketone scaffolds.
• Material Science Research: A precursor for developing organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Agrochemical Development: Employed in the synthesis of novel herbicides and fungicides with targeted activity.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological pathways and protein interactions.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	1-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Pent-4-En-1-One
CAS No.	2377606-47-6
Molecular Formula	C₁₇H₂₃BO₃
Molecular Weight	286.18 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzylideneacetone; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pent-4-en-1-one; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzalacetone; (4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pent-4-en-1-one; Boronic acid, B-[4-(3-butenoyl)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 1-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Pent-4-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹¹B), and GC/MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.