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(2-Chloro-5-Methylpyridin-4-Yl)Boronic Acid CAS NO 2377605-91-7


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CAS No.:2377605-91-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Chloro-5-Methylpyridin-4-Yl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated pyridine motifs.
  • Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boron reagent for forming carbon-carbon bonds with aryl or vinyl halides, a cornerstone of medicinal and process chemistry.
  • Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
  • Material Science Research: Acts as a monomer or functionalization agent in the development of organic electronic materials, such as those for OLEDs or conductive polymers.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and target engagement.

Basic Information

Product Name (2-Chloro-5-Methylpyridin-4-Yl)Boronic Acid
CAS No. 2377605-91-7
Molecular Formula C6H7BClNO2
Molecular Weight 171.39 g/mol
Synonyms 4-Borono-2-chloro-5-methylpyridine; 2-Chloro-5-methyl-4-pyridineboronic acid; (2-Chloro-5-methyl-4-pyridinyl)boronic acid; B-(2-Chloro-5-methyl-4-pyridinyl)boronic acid; 2-Chloro-5-methylpyridine-4-boronic acid; 4-Pyridineboronic acid, 2-chloro-5-methyl-
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Quality Control

Our (2-Chloro-5-Methylpyridin-4-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in demanding synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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