Description

4,4,5,5-Tetramethyl-2-(3-Oxabicyclo[4.1.0]Heptan-6-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block designed for sophisticated organic synthesis. This compound is valued for its unique strained bicyclic structure, which provides a versatile handle for cross-coupling reactions and the construction of complex molecular architectures. It is an essential intermediate for researchers and process chemists in pharmaceutical development, agrochemical discovery, and advanced materials science.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring complex, functionalized ring systems.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, polymers, and liquid crystals.
• Chemical Biology & Probe Development: Employed in the synthesis of bioconjugates and molecular probes for studying biological pathways and diagnostics.
• Catalyst Ligand Synthesis: Acts as a building block for constructing novel chiral or sterically hindered ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: A critical reagent for methodological development in organic chemistry and the exploration of new synthetic routes.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(3-Oxabicyclo[4.1.0]Heptan-6-Yl)-1,3,2-Dioxaborolane
CAS No.	2374751-49-0
Molecular Formula	C13H21BO3
Molecular Weight	236.12 g/mol
Synonyms	2-(3-Oxabicyclo[4.1.0]heptan-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-oxabicyclo[4.1.0]heptane; 3-Oxabicyclo[4.1.0]heptane-6-boronic acid, pinacol ester; Pinacol (3-oxabicyclo[4.1.0]hept-6-yl)boronate; (3-Oxabicyclo[4.1.0]hept-6-yl)boronic acid pinacol ester; Oxirane-fused Cyclohexyl Pinacol Boronate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 4,4,5,5-Tetramethyl-2-(3-Oxabicyclo[4.1.0]Heptan-6-Yl)-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be stored away from strong alkali and organic solvents. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
NMR Analysis	Conforms to structure (1H, 13C, 11B)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.