Description

tert-Butyl 6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Hexanoate is a high-purity, protected boronic ester derivative designed for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular frameworks. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific carbon-boron bond transformations.
• Material Science Research: Employed in the creation of organic electronic materials, polymers, and liquid crystals where the boronate ester functionality is incorporated.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for diagnostic and research applications.
• Process Chemistry: Valued in scale-up and route development for its stability and reactivity profile under various catalytic conditions.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	tert-Butyl 6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Hexanoate
CAS No.	2373347-25-0
Molecular Formula	C₁₆H₃₁BO₄
Molecular Weight	298.23 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)hexanoic acid tert-butyl ester; tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hexanoate; 2-(5-tert-Butoxycarbonylpentyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 6-(tert-butoxycarbonyl)hexylboronate; B-6-(tert-Butoxycarbonyl)hexylboronic acid pinacol ester; 6-(Boc)hexylBPin; Boc-C6-BPin
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Hexanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.