Description

3-Bromo-1-Chloro-5-Fluoro-4-Iodo-2-Methyl-Benzene is a highly functionalized, multi-halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an exceptionally valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by introducing halogenated aromatic motifs into lead structures.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: An essential reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution, enabling rapid diversification of molecular libraries.
• Ligand & Catalyst Development: Employed to synthesize novel chelating ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry: The presence of fluorine makes it valuable for studying structure-activity relationships (SAR) and metabolic stability in bioactive compounds.

Basic Information

Product Name	3-Bromo-1-Chloro-5-Fluoro-4-Iodo-2-Methyl-Benzene
CAS No.	2368909-47-9
Molecular Formula	C7H4BrClFI
Molecular Weight	363.37 g/mol
Synonyms	1-Bromo-3-chloro-5-fluoro-4-iodo-2-methylbenzene; 2-Methyl-3-bromo-1-chloro-5-fluoro-4-iodobenzene; 4-Iodo-3-bromo-1-chloro-5-fluoro-2-methylbenzene; BCFIMB (abbreviation); Halogenated Toluene Derivative; Multi-halogenated Benzene; 2368909-47-9 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-Chloro-5-Fluoro-4-Iodo-2-Methyl-Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.