Description

Benzoic Acid, 2-(Bromomethyl)-5-Formyl-3-(Trifluoromethyl)-, Methyl Ester is a high-value, multi-functional chemical intermediate characterized by its reactive bromomethyl, formyl, and trifluoromethyl groups. This compound matters for its versatility in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its reactive handles for further modification.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and labeled compounds for proteomics and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A critical intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Benzoic Acid, 2-(Bromomethyl)-5-Formyl-3-(Trifluoromethyl)-, Methyl Ester
CAS No.	2368845-05-8
Molecular Formula	C12H8BrF3O3
Molecular Weight	337.09 g/mol
Synonyms	Methyl 2-(bromomethyl)-5-formyl-3-(trifluoromethyl)benzoate; 2-(Bromomethyl)-5-formyl-3-(trifluoromethyl)benzoic acid methyl ester; 5-Formyl-2-(bromomethyl)-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 5-formyl-2-(bromomethyl)-3-(trifluoromethyl)benzoate; Benzoic acid, 2-(bromomethyl)-5-formyl-3-(trifluoromethyl)-, methyl ester; 2368845-05-8
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-(Bromomethyl)-5-Formyl-3-(Trifluoromethyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.