Description

5-Fluoro-3,3-Bis(4-Fluorophenyl)Benzo[C][1,2]Oxaborol-1(3H)-Ol is a high-value, fluorinated oxaborole derivative, a class of compounds renowned for their unique reactivity and utility in advanced chemical synthesis. This compound matters as a sophisticated building block or intermediate for pharmaceutical research and the development of novel materials, where the incorporation of fluorine and the oxaborole moiety can dramatically alter biological activity and physical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries working on new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Boronic Acid/Ester Alternative: Used in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to construct complex biaryl structures.
• Protease Inhibitor Research: The oxaborole core is a known pharmacophore for the development of enzyme inhibitors, including serine proteases.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties.
• Agrochemical Synthesis: Employed in the research and development of new generation pesticides and herbicides.
• Chemical Biology Probe: Utilized in the design of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	5-Fluoro-3,3-Bis(4-Fluorophenyl)Benzo[C][1,2]Oxaborol-1(3H)-Ol
CAS No.	2366993-30-6
Molecular Formula	C20H12B1F3O2
Molecular Weight	352.12 g/mol
Synonyms	5-Fluoro-3,3-bis(4-fluorophenyl)-3H-1,2-benzoxaborol-1-ol; 5-Fluoro-3,3-bis(4-fluorophenyl)-1-hydroxy-1,2-benzoxaborole; 5-Fluoro-3,3-bis(p-fluorophenyl)-1-hydroxybenzo[c][1,2]oxaborole; 1-Hydroxy-5-fluoro-3,3-bis(4-fluorophenyl)-1,2-benzoxaborol-3-ium-1-uide; CAS 2366993-30-6; Fluorinated Oxaborole Derivative
EINECS	Contact for details

Quality Control

Every batch of our 5-Fluoro-3,3-Bis(4-Fluorophenyl)Benzo[C][1,2]Oxaborol-1(3H)-Ol is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.