Description

Cyclohexanecarboxylic Acid, 4-[(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methylene]-, Ethyl Ester is a high-value, advanced pharmaceutical intermediate and building block featuring a versatile boronic ester functional group. This compound is critical for enabling key synthetic transformations, particularly in the construction of complex molecular architectures via cross-coupling reactions. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boron-containing coupling partner for the synthesis of biaryl and conjugated systems in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), especially those requiring complex, functionalized cyclohexane cores.
• Agrochemical Synthesis: Employed as a building block for creating new herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Utilized in the synthesis of organic electronic materials, ligands for catalysis, and other specialty polymers.
• Chemical Biology & Proteomics: Acts as a probe or linker in the development of chemical tools for studying biological systems.
• Process Chemistry & Scale-up: Provides a stable, handleable boronate source for optimizing large-scale manufacturing routes for fine chemicals.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-[(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methylene]-, Ethyl Ester
CAS No.	2365173-46-0
Molecular Formula	C16H27BO4
Molecular Weight	294.20 g/mol
Synonyms	4-[(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methylene]cyclohexanecarboxylic acid ethyl ester; Ethyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)cyclohexanecarboxylate; 4-Pinacolatoborylmethylene-cyclohexanecarboxylic acid ethyl ester; 4-[(Pinacolatoboryl)methylene]cyclohexanecarboxylic Acid Ethyl Ester; Cyclohexanecarboxylic acid, 4-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene]-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of our Cyclohexanecarboxylic Acid, 4-[(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methylene]-, Ethyl Ester is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.