Description

6-Borono-5-Methoxy-1H-Indazole is a high-purity, functionalized indazole derivative containing a boronic acid group. This compound serves as a critical pharmaceutical intermediate and building block in modern synthetic chemistry, enabling the construction of complex molecules through cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted cancer therapies.
• Suzuki-Miyaura Cross-Coupling: Essential boron-containing reagent for forming carbon-carbon bonds in medicinal chemistry and material science research.
• Kinase Inhibitor Development: Used as a core scaffold or substituent in the design and synthesis of potent kinase inhibitors.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with novel modes of action.
• Material Science: Building block for advanced organic materials, such as organic light-emitting diodes (OLEDs) or sensors.

Basic Information

Product Name	6-Borono-5-Methoxy-1H-Indazole
CAS No.	2304635-77-4
Molecular Formula	C8H9BN2O3
Molecular Weight	192.00 g/mol
Synonyms	5-Methoxy-1H-indazole-6-boronic acid; 6-Borono-5-methoxy-1H-indazole; 5-Methoxy-6-boronoindazole; 1H-Indazole-6-boronic acid, 5-methoxy-; (5-Methoxy-1H-indazol-6-yl)boronic acid; 2304635-77-4; 6-Borono-5-methoxyindazole
EINECS	Contact for details

Quality Control

Our 6-Borono-5-Methoxy-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and must be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.