Description

{1H‐Pyrrolo[2,3‐B]Pyridin‐2‐Yl}Boronic Acid Hydrochloride is a high-purity boronic acid derivative and a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic cores found in drug candidates targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds between aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	{1H‐Pyrrolo[2,3‐B]Pyridin‐2‐Yl}Boronic Acid Hydrochloride
CAS No.	2304635-61-6
Molecular Formula	C7H8BClN2O2
Molecular Weight	198.41 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridin-2-ylboronic acid hydrochloride; 2-(1H-Pyrrolo[2,3-b]pyridin-2-yl)boronic acid HCl; 7-Azaindole-2-boronic acid hydrochloride; 1H-Pyrrolo[2,3-b]pyridine-2-boronic acid hydrochloride salt; 2-Borono-1H-pyrrolo[2,3-b]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of {1H‐Pyrrolo[2,3‐B]Pyridin‐2‐Yl}Boronic Acid Hydrochloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.